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KMID : 0390020120220010116
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Pediatric Allergy and Respiratory Disease
2012 Volume.22 No. 1 p.116 ~ p.121
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A Case Report of Food-Dependent Exercise-Induced Anaphylaxis in a Patient who was Sensitive to Pork
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Pang Sung-Joon
No Sol-Ji
Kim Dong-Wook
Lee Sang-Min
Lee Eun-Jeong
Kim Cheol-Hong
Lee Hyun-Hee
Lee Kyung-Eun
Hong Jeong-Yeon
Kim Kyu-Earn
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Abstract
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Food-dependent exercise-induced anaphylaxis (FDEIA) is a specific variant of exercise-induced anaphylaxis that requires both vigorous physical activity and the ingestion of specific foods. In particular, it is rare occurrence for FDEIA to be associated with meat in Korea. A 15-year-old female had generalized urticaria, dyspnea, severe cough, headache, dizziness, and vomiting after singing and dancing for 1 hour and after ingesting grilled pork. Skin prick tests showed a strong positive reaction to pork, whereas the results of an oral food challenge and exercise provocation tests were negative. However, the exercise provocation test after pork ingestion showed a positive reaction manifested by generalized urticaria, cough, mild dyspnea, and a 23% decreased peak expiratory flow rate. Three allergens to pork (67 kDa, 90 kDa, and 15 kDa) reacted with the patient’s serum on immunoglobulin E immunoblotting. We report a case of pork-dependent exercise-induced anaphylaxis in a patient who was sensitive to pork.
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KEYWORD
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Food allergy, Sensitization to pork, Food-dependent exercise-induced anaphylaxis (FDEIA)
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